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Maya Saleh Publications

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Crosstalk between the intestinal microbiota and the innate immune system in intestinal homeostasis and inflammatory bowel disease
Dupaul-Chicoine J, Dagenais M, Saleh M.
Inflamm Bowel Dis. 2013 Sep;19(10):2227-37. doi: 10.1097/MIB.0b013e31828dcac7.
PMID: 23669404 [PubMed - in process]
Related citations:
Select item 23069594

aspases and immunity in a deadly grip
Rodrigue-Gervais IG, Saleh M.
rends Immunol. 2013 Feb;34(2):41-9. doi: 10.1016/j.it.2012.09.005. Epub 2012 Oct 12.
PMID: 23069594 [PubMed - in process]
elated citations: S
elect item 22344277

A new path to IL-1β production controlled by ca
upaul-Chicoine J, Saleh M.
t Immunol. 2012 Feb 16;13(3):211-2. doi: 10.1038/ni.2241. No abstract available.
PMID: 22344277 [PubMed - indexed for MEDLINE]
lated citations: Se
lect item 22195745

Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient cas
pase-1 activation by the inflammasome
bbé K, McIntire CR, Doiron K, Leblanc PM, Saleh M.
unity. 2011 Dec 23;35(6):897-907. doi: 10.1016/j.immuni.2011.10.016.
PMID: 22195745 [PubMed - indexed for MEDLINE]
ated citations: Sel
ect item 21552281

Non-apoptotic role of BID in inflammation and innate immunity.
etssian G, Correa RG, Doiron K, Fitzgerald P, Dillon CP, Gree
n DR, Reed JC, Saleh M.
re. 2011 Jun 2;474(7349):96-9. doi: 10.1038/nature09982. Epub 2011 May 8.
PMID: 21552281 [PubMed - indexed for MEDLINE]
ted citations

Experimental inflammatory bowel disease: insights into the host-microbiota dialog.

Saleh M, Elson CO.

Immunity. 2011 Mar 25;34(3):293-302.


Stromal retinoic acid receptor beta promotes mammary gland tumorigenesis.

Liu X, Nugoli M, Laferrière J, Saleh SM, Rodrigue-Gervais IG, Saleh M, Park M, Hallett MT, Muller WJ, Giguère V.

Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):774-9. Epub 2010 Dec 27.


Function of NOD-like receptors in immunity and disease.

Dagenais M, Dupaul-Chicoine J, Saleh M.

Curr Opin Investig Drugs. 2010 Nov;11(11):1246-55.


Innate immune mechanisms of colitis and colitis-associated colorectal cancer.

Saleh M, Trinchieri G.

Nat Rev Immunol. 2011 Jan;11(1):9-20. Epub 2010 Dec 10. Review.


Caspase-12 deficiency enhances cytokine responses but does not protect against lethal Plasmodium yoelii 17XL infection.

Miu J, Saleh M, Stevenson MM.

Parasite Immunol. 2010 Nov-Dec;32(11-12):773-8.


Caspase-12 dampens the immune response to malaria independently of the inflammasome by targeting NF-kappaB signaling.

Labbé K, Miu J, Yeretssian G, Serghides L, Tam M, Finney CA, Erdman LK, Goulet ML, Kain KC, Stevenson MM, Saleh M.

J Immunol. 2010 Nov 1;185(9):5495-502. Epub 2010 Sep 27.


Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I.

Wang P, Arjona A, Zhang Y, Sultana H, Dai J, Yang L, LeBlanc PM, Doiron K, Saleh M, Fikrig E.

Nat Immunol. 2010 Oct;11(10):912-9. Epub 2010 Sep 5.


Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases.

Dupaul-Chicoine J, Yeretssian G, Doiron K, Bergstrom KS, McIntire CR, LeBlanc PM, Meunier C, Turbide C, Gros P, Beauchemin N, Vallance BA, Saleh M.

Immunity. 2010 Mar 26;32(3):367-78. Epub 2010 Mar 11.


Genetics of inflammasome-associated disorders: a lesson in the guiding principals of inflammasome function.

Rodrigue-Gervais IG, Saleh M.

Eur J Immunol. 2010 Mar;40(3):643-8. Review.


Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4.

Fortier A, Doiron K, Saleh M, Grinstein S, Gros P.

Infect Immun. 2009 Nov;77(11):4794-805. Epub 2009 Aug 31.


Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.

Bertrand MJ, Doiron K, Labbé K, Korneluk RG, Barker PA, Saleh M.

Immunity. 2009 Jun 19;30(6):789-801. Epub 2009 May 21.


Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection.

Yeretssian G, Doiron K, Shao W, Leavitt BR, Hayden MR, Nicholson DW, Saleh M.

Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9016-20. Epub 2009 May 15.


Inflammasomes in infection and inflammation.

McIntire CR, Yeretssian G, Saleh M.

Apoptosis. 2009 Apr;14(4):522-35. Review.


Molecular regulation of inflammation and cell death.

Yeretssian G, Labbé K, Saleh M.

Cytokine. 2008 Sep;43(3):380-90. Epub 2008 Aug 13. Review.


Cell death in the host response to infection.

Labbé K, Saleh M.

Cell Death Differ. 2008 Sep;15(9):1339-49. Epub 2008 Jun 20. Review.


Confinement of caspase-12 proteolytic activity to autoprocessing.

Roy S, Sharom JR, Houde C, Loisel TP, Vaillancourt JP, Shao W, Saleh M, Nicholson DW.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4133-8. Epub 2008 Mar 10.


Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity.

LeBlanc PM, Yeretssian G, Rutherford N, Doiron K, Nadiri A, Zhu L, Green DR, Gruenheid S, Saleh M.

Cell Host Microbe. 2008 Mar 13;3(3):146-57.


Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis.

Mazroui R, Di Marco S, Clair E, von Roretz C, Tenenbaum SA, Keene JD, Saleh M, Gallouzi IE.

J Cell Biol. 2008 Jan 14;180(1):113-27. Epub 2008 Jan 7.


The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock.

Shao W, Yeretssian G, Doiron K, Hussain SN, Saleh M.

J Biol Chem. 2007 Dec 14;282(50):36321-9. Epub 2007 Oct 24.


Caspase-1 inflammasomes: choosing between death and taxis.

Saleh M, Green DR.

Cell Death Differ. 2007 Sep;14(9):1559-60. No abstract available.


Caspase-1 builds a new barrier to infection.

Saleh M.

Cell. 2006 Sep 22;126(6):1028-30. Review.


The inflammatory caspases: key players in the host response to pathogenic invasion and sepsis.

Nadiri A, Wolinski MK, Saleh M.

J Immunol. 2006 Oct 1;177(7):4239-45. Review.


The inflammatory caspases: guardians against infections and sepsis.

Scott AM, Saleh M.

Cell Death Differ. 2007 Jan;14(1):23-31. Epub 2006 Sep 15. Review.


Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice.

Saleh M, Mathison JC, Wolinski MK, Bensinger SJ, Fitzgerald P, Droin N, Ulevitch RJ, Green DR, Nicholson DW.

Nature. 2006 Apr 20;440(7087):1064-8.


Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis.

Spierings D, McStay G, Saleh M, Bender C, Chipuk J, Maurer U, Green DR.

Science. 2005 Oct 7;310(5745):66-7.


Axonal dynactin p150Glued transports caspase-8 to drive retrograde olfactory receptor neuron apoptosis.

Carson C, Saleh M, Fung FW, Nicholson DW, Roskams AJ.

J Neurosci. 2005 Jun 29;25(26):6092-104.


Life support: the alpha4 phosphatase subunit in cell survival and apoptosis.

Saleh M, Pagliari LJ, Green DR.

Trends Cell Biol. 2005 Jun;15(6):285-7.


Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms.

Saleh M, Vaillancourt JP, Graham RK, Huyck M, Srinivasula SM, Alnemri ES, Steinberg MH, Nolan V, Baldwin CT, Hotchkiss RS, Buchman TG, Zehnbauer BA, Hayden MR, Farrer LA, Roy S, Nicholson DW.

Nature. 2004 May 6;429(6987):75-9.


Substrate cleavage by caspases generates protein fragments with Smac/Diablo-like activities.

Hell K, Saleh M, Crescenzo GD, O'Connor-McCourt MD, Nicholson DW.

Cell Death Differ. 2003 Nov;10(11):1234-9.