Nancy Mayo has two major research programs: one on stroke and one related to health services and outcomes research. The unifying theme of her research is outcome measurement and improvement and use of administrative databases for clinical research. In the arena of health services and outcomes research, she has applied knowledge of modeling time to discharge to waiting time for breast cancer surgery and examined variation in waiting time and also in stroke hospitalization outcomes.

She has conducted a number of clinical trials on service delivery for persons with stroke and has just completed a large database study with Dr Bruno Gagnon on end-of-life care for women dying of breast cancer. In the area of stroke, she has investigated the impact of stroke on the individual, the family and society. This led her to do research in the area of outcomes: impairments, disability, handicap, and QOL, as well as on the impact on caregivers and society at large, in terms of population burden. This research program pointed out gaps in the care that stroke patients receive and led to a series of clinical trials evaluating care-delivery models (home-based rehabilitation, case-management to enhance continuity of care, late rehabilitation), cost-effectiveness and policy implications.

Mayo's future research will flow from her ongoing studies, with an emphasized focus on end-of-life care both for people with cancer and those dying of chronic circulatory diseases.

Her active grants include :

CIHR-Grant title : Palliative Care Cancer Research - The major goal of this projects is to improve the quality of life of people with cancer and their families.

CIHR -Grant title: E-Integration in the Management of Respiratory and Circulatory Disease - This project aims at building the foundations of an emerging scientific discipline in e-integration for chronic disease management by bringing together scientists from the research disciplines of management, marketing, consumer psychology, epidemiology and clinical medicine to study experimental prototypes of e-integration for asthma and stroke on the quality and outcome of care.

CIHR-Grant title :Turning temporarily salient health threats into catalysts for healthier lifestyle: The case of women with benign outcomes to breast cancer anomaly. - The major goal of this project is to use an emotional appeal in health information in computer-based interactive communication tools (CICT) to adult women who have just received a benign outcome from breast cancer anomaly screening is more effective in: (1) assisting the women to recover psychologically from the temporary salient health threat and (2) inducing healthier lifestyle behaviors and enduring intent to perform early detection behaviors, after having enticed women to attend more to health information in the first place.

CIHR Grant title : Estimating age, gender and risk factor-specific incidence rate of strokes and heart disease using longitual cohorts ejected from linkage of survey and administrative databases - The major goal of this project is to estimate the incidence of stroke in Quebec and the extent to which common risk factors (hypertension, smoking, alcohol consumption, and obesity) and unexplored risk factors (stress, anxiety and health service utilization) modify the occurrence of stroke in Quebec adults.

CFI Grant title : Quebec Integrated Health Research Network - The major goal of this projects are to develop prototypes for clinical informatics systems.

CIHR Grant Title :The WOW Health Study: “What older women to age wisely” want: A National Survey on older women’s preventive health care. The major goal of this project is to conduct a national survey of Canadian women over the age of 55 to understand women's health priorities to optimize physical, emotional and social well-being during their later years.

CFDR Grant title: Use and perceptions of Glycemic index by Canadian dieticians in the nutritional management of diabetes -.The major goal of this projects will investigate a wide spectrum of topics important in the prevention and treatment of nutrition-related illnesses.

National Centre of Excellence Grant Title: Canadian Stroke Network - The major goal of this project is to bring together over 100 researchers across Canada to carry our research on stroke prevention, clinical care, reducing cell damage, brain repair and recovery.

CSN Grant title: Effectiveness of Rehabilitation in Stroke: Manual Dexterity and Walking Competency Post-Stroke: A Randomized Controlled Trial - The major goal of this project is to determine whether an intensive, task-specific gait rehabilitation program is effective in improving competence in walking post-stroke. A randomized clinical trial is proposed.

Canadian Stroke Network Grant title: Predicting the Brain’s Capacity to Reorganize after Acute Stroke: A Study of Physiological, Anatomical, Clinical and Behavioral Parameters.- The major goal of this projects are to identify a profile of pre-morbid and early anatomical, physiological and clinical characteristics, reflective of brain structure and function, that predict, at the individual level, the restoration of normal, near normal or compensatory activity; and to estimate the degree of concordance between the prediction of recovery from the clinical profile and from neuro-imaging measures of the degree to which the brain reorganizes post-stroke.

Canadian Stroke Network Grant title: Understanding Health Related Quality of Life of Stroke Patients and their Caregivers. - The major goal of this project is to build and empirically test a biopsychosocial conceptual model of HRQL for people with stroke and for family caregivers.

VRQ Grant Title : Cyber Santé. - The major goal of this project is to develop the information systems (infrastructure) that will support the use of IRIS (the infrastructure) for heath care and research.

Her pending gtrants include:

CIHR Grant Title :Fitness Intervention on Trial Post Stroke (FITS): Enhancing walking endurance using home rehabilitation.-The major goal of this project is to evaluate, among persons who have completed the restorative phase of stroke and have ceased formal rehabilitation, the relative effectiveness in improving endurance of two programs for continued care, a home-based general fitness training program using stationary cycling and a disability targeted home-based walking competency program of walking and mobility tasks.

CIHR Grant Title- Patterns of Care During the Last 6 Months of Life of Patients Dying of Cancer: a Study Using Administrative Data. - The major goal of this project is to estimate the extent to which the patterns of care received by patients dying of cancer during their last six months of life reflect health care services in keeping with a palliative care oriented approach, and to determine the clinical, societal and health care system factors modifying access to care-oriented end of life care.

CIHR-RCT Grant title : Enhancing the outcome after colonic surgery. The role of prehabilitation. - The major goal of this project is to address the following research question: Among persons scheduled for colorectal surgery, does a pre-operative program of aerobic and muscle strength training (prehabilitation) above a standard pre-operative educational and nutritional protocol affect functional exercise capacity and health-related quality of life post-surgery?

CIHR Grant title : The occurrence of arm dysfunction and lymphedema after treatment for stage I and II breast cancer.- The major goal of this projects are to estimate the prevalence of arm dysfunction and lymphedema to identify risk factors, and to evaluate quality of life.

CIHR Grant title : Integration of the International Classification of Functioning (ICF) into electronic health records and administrative databases: Methodology to create a standard coded list of problem-indicators. - The major goal of this project is to integrate into medical charts a set of common functional status indicators that will cross disciplines and diseases.

CIHR- Advancing Theories Grant title: Development and testing of a physiological index of disease severity suitable for integration into electronic health records and administrative databases to improve the outcome prediction and case-mix adj.- The major goal of this projects is to examine the incremental value in the prediction of both short and long term health outcomes by incorporating additional clinical information.

Dr. Nancy Mayo can be reached at:

Nancy E. Mayo, BSc.(PT), MSc, PhD., James McGill Professor

Department of Medicine, School of Physical and Occupational Therapy

McGill University Division of Clinical Epidemiology, Division of Geriatrics

McGill University Health Center

Royal Victoria Hospital Ross Pavilion R4.29687

Pine Ave West

Montreal, QC, H3A 1A1

Tel. (514) 842 1231 36922

FAX (514) 843 1493

Email: nancy.mayo@mcgill.ca.