Associate Professor
Institute of Parasitology
Macdonald Campus, McGill University
21,111 Lakeshore Road
Ste. Anne de Bellevue, Qc, H9X 3V9
Tel.: 514-398-7607
Fax: 514-398-7857
paula [dot] ribeiro [at] mcgill [dot] ca (Email)
Research interests
Helminth neurobiology and biochemistry; molecular biology of serotonin receptors and associated pathways of signal transduction in helminths; role of neurotransmitter receptors in mediating anthelmintic pharmacology and resistance.
Graduate student positions
Vacancies for PhD and/or MSc positions in molecular parasitology
Positions are available immediately to study mechanisms of signal transduction in the parasitic worm, Schistosoma mansoni, and the model nematode, Caenorhabditis elegans. Projects include an investigation of neurotransmitter G protein -coupled receptors (GPCR), using a combination of functional genomics and proteomics. Applicants must have strong undergraduate training in molecular biology or biochemistry. For enquiries, please contact Dr. Paula Ribeiro, Institute of Parasitology, McGill University paula [dot] ribeiro [at] mcgill [dot] ca (Email)
Selected Publications
- Dernovici S., Starc T., Dent J.A., Ribeiro P. (2007)
- The Serotonin Receptor SER-1 (5HT2ce) Contributes to the Regulation of Locomotion in Caenorhabditis elegans. Journal of Neurobiology (preview).
- Dernovici S, Starc T, Dent JA, Ribeiro P. (2007)
- The serotonin receptor SER-1 (5HT2ce) contributes to the regulation of locomotion in Caenorhabditis elegans. Dev Neurobiol. 67:189-204.
- Nabhan J F, Ribeiro P (2006)
- The 19s proteasomal subunit poh1 contributes to The regulation of c-jun ubiquitination, stability And subcellular localization. J. Biol. Che. 281: 16099-16107
- Ribeiro P, El-Shehabi, F Patocka N.(2005)
- Classical transmitters and their receptors in flatworms. Parasitology131 Suppl:S19-40.
- Xie J. Dernovici S. Ribeiro P. (2005)
- Mutagenesis analysis of the serotonin 5-HT2C receptor and a Caenorhabditis elegans 5-HT2 homologue: conserved residues of helix 4 and helix 7 contribute to agonist-dependent activation of 5-HT2 receptors. Journal of Neurochemistry . 92(2):375-87,
- Bouchard C. Ribeiro P. Dube F. Demers C. Anctil M. (2004)
- Identification of a novel aminergic-like G protein-coupled receptor in the cnidarian Renilla koellikeri. Gene 341:67-75.
- Bouchard, C., Ribeiro, P., Dube, F. and Anctil, M. (2003)
- A New G protein-coupled receptor from a primitive metazoan shows homology with vertebrate aminergic receptors and displays constitutive activity in mammalian cells. J. Neurochem, 86: 1149-1161.
- Spithill TW, Chadee K, Jardim AP, Prichard RK, Ribeiro P.(2002).
- Confronting parasite from Canada. Trends in Parasitology. 18: 519-521.
- Hamdan FF, Abramovitz M, Mousa A, Xie J, Durocher Y et al. (2002)
- A novel Schistosoma mansoni G protein-coupled receptor is responsive to histamine. Mol Biochem Parasitol 119: 75-86.
- Hamdan FF, Mousa A and Ribeiro P (2002)
- Codon optimization improves heterologous expression of a Schistosoma mansoni cDNA in HEK293 cells. Parasitology Research 88: 583-586, 2002.
- Nabhan JF, Hamdan FF and Ribeiro P (2002)
- A Schistosoma mansoni Pad1 homologue stabilizes c-Jun. Mol Biochem Parasitol 121: 163-172.