Quick Links

Elias Georges

Associate Professor

Institute of Parasitology

Photo

McGill University
21,111 Lakeshore Road
Ste. Anne de Bellevue, Qc, H9X 3V9

Tel.: 514-398-8137
Fax: 514-398-7857
elias [dot] georges [at] mcgill [dot] ca (Email)

Research interests

Multidrug resistance in human cancer cells and Plasmodium falciparum: drug targeting of surface proteins mediating human diseases; antibody engineering for immunotherapeutic treatment.

Selected Publications

Leimanis ML, Karwatsky J, Georges E.
Photoaffinity labeling of the multidrug resistance protein 2 (ABCC2/cMOAT) with a photoreactive analog of LTC(4). Int J Biochem Mol Biol. 2011;2(1):39-46. Epub 2010 Dec 15.

Laberge RM, Ambadipudi R, Georges E.
P-glycoprotein (ABCB1) modulates collateral sensitivity of a multidrug resistant cell line to verapamil. Arch Biochem Biophys. 2009 Nov;491(1-2):53-60. Epub 2009 Sep 20.

Bellemare MJ, Bohle DS, Brosseau CN, Georges E, Godbout M, Kelly J, Leimanis ML, Leonelli R, Olivier M, Smilkstein M.
Autofluorescence of condensed heme aggregates in malaria pigment and its synthetic equivalent hematin anhydride (beta-hematin). J Phys Chem B. 2009 Jun 18;113(24):8391-401.

Georges E.
The P-glycoprotein (ABCB1) linker domain encodes high-affinity binding sequences to alpha- and beta-tubulins. Biochemistry. 2007 Jun 26;46(25):7337-42. Epub 2007 May 27.

Laberge RM, Karwatsky J, Lincoln MC, Leimanis ML, Georges E.
Modulation of GSH levels in ABCC1 expressing tumor cells triggers apoptosis through oxidative stress. Biochem Pharmacol. 2007 Jun 1;73(11):1727-37. Epub 2007 Feb 15.

Leimanis ML, Georges E.
ABCG2 membrane transporter in mature human erythrocytes is exclusively homodimer.Biochem Biophys Res Commun. 2007 Mar 9;354(2):345-50. Epub 2007 Jan 9.

 

Publications - Elias Georges