Assistant Professor
B.Sc. (Carleton University, 2007)
Ph.D. (Carleton University, 2012)
NSERC Postdoctoral Fellow (Stanford University, 2012-2016)
Researcher/Lecturer (ETH Zürich, 2016-2018)
Associate Editor, Molecular Therapy-Nucleic Acids, 2022-present
Kavli Emerging Leader in Chemistry, American Chemical Society, 2021
Canada Research Chair Tier II, CIHR in Genomic Chemistry, 2019-present
Executive Editor Aptamers, Library Publishing Media, 2020-present
Editor Advisory Board, ACS Chemical Research in Toxicology, 2021-2023
Office: P&P 104
Lab: OM 400; McMed 1317
Lab Phone: 514-398-1689
Email: Maureen.Mckeague [at] McGill.CA
Website: McKeague Group Website
Research Themes
- Analytical/ Environmental
- Chemical Biology
- Green and Sustainable Chemistry
Research Interests
Chemical Genomics
The chemistry of the genome is far more complex than the base pairing recognition of A-T and G-C. For example, small modifications to each base (e.g., DNA damage and epigenetic marks) profoundly impact a cell’s ability to proliferate and produce secondary metabolites. On the other hand, direct binding of small molecules to DNA or RNA can be used to regulate biosynthetic pathways. Our research bridges the chemistry of the genome to natural product production and clinical diagnostics for new applications in green chemistry and cancer therapeutics.
Currently Teaching
CHEM 110
General Chemistry 1
4 Credits
Offered in the:
- Fall
- Winter
- Summer
Chemistry: A study of the fundamental principles of atomic structure, radiation and nuclear chemistry, valence theory, coordination chemistry, and the periodic table.
Offered by: Chemistry
- Fall
- Prerequisites/corequisites: College level mathematics and physics or permission of instructor; CHEM 120 is not a prerequisite
- Each lab section is limited enrolment
- Terms
- This course is not scheduled for the 2024 academic year
- Instructors
- There are no professors associated with this course for the 2024 academic year
PHAR 303
Principles of Toxicology
3 Credits
Offered in the:
- Fall
- Winter
- Summer
Pharmacology and Therapeutics: Fundamental mechanisms by which toxic compounds damage a biological system (organelle, cell, organ, organism, ecosystem). Detection and quantification of toxicity and risk/benefit analysis are considered. Selected agents of current risk to human health or the environment are evaluated in depth.
Offered by: Pharmacology and Therapeutics
- Terms
- This course is not scheduled for the 2024 academic year
- Instructors
- There are no professors associated with this course for the 2024 academic year
PHAR 702
Topics in Pharmacology 1
3 Credits
Offered in the:
- Fall
- Winter
- Summer
Pharmacology and Therapeutics: Topics in pharmacology.
Offered by: Pharmacology and Therapeutics
- Prerequisite: Permission of the Instructor.
- Terms
- This course is not scheduled for the 2024 academic year
- Instructors
- There are no professors associated with this course for the 2024 academic year