By Tod Hoffman, Lady Davis Institute Research reveals that even a tiny mutation can allow the HIV virus to become resistant to therapies using the CRISPR/Cas9 gene-editing platform
A Canadian research team at the IRCM in Montréal, led by molecular virologist Éric A. Cohen, PhD, made a significant discovery on how HIV escapes the body’s antiviral responses. The team uncovered how an HIV viral protein known as Vpu tricks the immune system by using its own regulatory process to evade the host’s first line of defence. This breakthrough was published yesterday in the scientific journal PLoS Pathogens and will be presented at the upcoming IAS 2015 conference in Vancouver. The findings pave the way for future HIV prevention or cure strategies.
Domestic violence takes many forms. The control of a woman’s reproductive choices by her partner is one of them. A major study published in PLOS One, led by McGill PhD student Lauren Maxwell, showed that women who are abused by their partner or ex-partner are much less likely to use contraception; this exposes them to sexually transmitted diseases and leads to more frequent unintended pregnancies and abortions. These findings could influence how physicians provide contraceptive counselling.
Here is a list of experts from McGill, the McGill University Health Centre (MUHC) and the Lady Davis Institute of the Jewish General Hospital available for comment on your stories for World AIDS Day:
November 27, 2012 - Clinician-scientists take a unique, integrated approach that is essential to advancing science and medicine. Problems encountered in the clinic inspire research and new findings from the labs are directly applied to patients’ needs. The integrated model is a hallmark of the Montreal Neurological Institute and Hospital – The Neuro, at McGill University and the MUHC and is now being replicated worldwide.