Assessing the risks that toxic chemicals pose to natural ecosystems is a huge challenge, given the thousands of chemicals that require testing. But the task is expected soon to become less daunting, thanks to a new tool being developed by McGill University researchers.
One of the great mysteries in biology is how the many different cell types that make up our bodies are derived from a single cell and from one DNA sequence, or genome. We have learned a lot from studying the human genome, but have only partially unveiled the processes underlying cell determination. The identity of each cell type is largely defined by an instructive layer of molecular annotations on top of the genome – the epigenome – which acts as a blueprint unique to each cell type and developmental stage.
A receptor for the dopamine neurotransmitter promotes growth and spread of pancreatic cancer -- and schizophrenia drugs, which block the function of this receptor, slowed tumor growth and metastatic spread in mice, according to researchers at McGill University and the German Cancer Research Center.
Génome Québec is happy to report that Québec has achieved excellent results in the 5th cycle of the Genomic Applications Partnership Program (GAPP).
Discovery of how environmental memories may be transmitted from a man to his grandchildren
Poultry used to be the usual suspect in cases of Salmonella poisoning. Today, however, most outbreaks of the illness come from fruit and vegetables that have become infected when the soil in which they grow is polluted by animal waste or non-potable water. There currently is no method of reducing the growth of Salmonella on such produce.
Researchers from Canada, the UK, Sweden and the US have discovered more than 30 genes that strongly affect an antibody involved in allergies and asthma. Some of the genes could provide targets for drugs to treat those conditions, according to the international team’s study, published online in Nature on Feb. 18.
A new study on a large cohort of kidney cancer patients in Europe sheds light on the genetic architecture of the disease -- and reveals an apparent link between exposure to aristolochic acid and incidence of kidney cancer, particularly in Romania.
Researchers from Quebec are big winners in a contest organized by Genome Canada in collaboration with the Canadian Institutes of Health Research (CIHR) after having been awarded 60% of the federal funds granted during this Canada-wide competition aimed at selecting the best genomics and personalized health research projects.