Djavad Mowafaghian Foundation shares The Neuro’s open science vision to accelerate drug discovery and find new and effective treatments for autism spectrum disorders

Classified as: Montreal Neurological Institute, The Neuro, open science, Open Drug Discovery Platform, autism, ASD, Guy Rouleau
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Published on: 29 May 2018

Abnormalities shown to first appear in brain networks involved in sensory processing

The origins of autism remain mysterious. What areas of the brain are involved, and when do the first signs appear? New findings published in Biological Psychiatry brings us closer to understanding the pathology of autism, and the point at which it begins to take shape in the human brain. Such knowledge will allow earlier interventions in the future and better outcomes for autistic children.

Classified as: autism, IBIS, Alan Evans, John Lewis, Ludmer Centre, ASD
Published on: 29 Aug 2017

Researchers from McGill University and the University of Montreal have identified a crucial link between protein synthesis and autism spectrum disorders (ASD), which can bolster new therapeutic avenues. Regulation of protein synthesis, also termed mRNA translation, is the process by which cells manufacture proteins. This mechanism is involved in all aspects of cell and organism function. A new study in mice has found that abnormally high synthesis of a group of neuronal proteins called neuroligins results in symptoms similar to those diagnosed in ASD. The study also reveals that autism-like behaviors can be rectified in adult mice with compounds inhibiting protein synthesis, or with gene-therapy targeting neuroligins. Their results are published in the journal Nature.

Classified as: Research, autism, Christos Gkogkas, Nahum Sonenberg, ASD
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Published on: 21 Nov 2012
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