Tuesday, April 2, 2024 13:00to14:30

Abstract:

Ferroptosis is form of cell death driven by peroxidation of specific lipids. I will briefly discuss the history, key regulators, recent emerging mechanisms, and therapeutic applications of controlling ferroptosis. I will describe how my lab recently identified an unusual species of lipid that is a key driver of ferroptosis, and how our studies linking ferroptosis to metabolism have enabled to design precision, therapeutic diets that promote ferroptosis in some cancer models.

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