BIC Lecture Series - Functional changes in encoding and retrieval networks that underlie successful context memory across the adult lifespan - Lizzy Ankudowich
By Bruno Geoffroy
For decades, scientists have fiercely debated whether rapid eye movement (REM) sleep – the phase where dreams appear – is directly involved in memory formation.
Now, a study published in Science by researchers at the Douglas Mental Health University Institute (McGill University) and the University of Bern provides evidence that REM sleep does, indeed, play this role – at least in mice.
Why is it that some people have richly detailed recollection of past experiences (episodic memory), while others tend to remember just the facts without details (semantic memory)?
A research team from the Rotman Research Institute at Baycrest Health Sciences has shown for the first time that these different ways of experiencing the past are associated with distinct brain connectivity patterns that may be inherent to the individual and suggest a life-long “memory trait”.
The study was recently published online in the journal Cortex.
McGill researchers have discovered, for the first time, the importance of a key epigenetic regulator in the development of the hippocampus, a part of the brain associated with learning, memory and neural stem cells. Epigenetic regulators change the way specific genes function without altering their DNA sequence. By working with mutant mice as models, the research team, led by Prof. Xiang-Jiao Yang, of McGill’s Goodman Cancer Center & Department of Medicine, McGill University Health Center, was able to link the importance of a specific epigenetic regulator known as BRPF1 to the healthy development of a region in the hippocampus called the dentate gyrus.
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A study just published in the prestigious Nature Neuroscience journal by, Sylvain Williams, PhD, and his team, of the Research Centre of the Douglas Mental Health University Institute and McGill University, opens the door towards better understanding of the neural circuitry and dynamic mechanisms controlling memory as well of the role of an essential element of the hippocampus – a sub-region named the subiculum.
Dr. Brenda Milner, an active researcher at the age of 95 at the Montreal Neurological Institute and Hospital - The Neuro, McGill University, is a recipient of The 2014 Kavli Prize in Neuroscience.
Research from McGill University reveals that the brain’s motor network helps people remember and recognize music that they have performed in the past better than music they have only heard. A recent study by Prof. Caroline Palmer of the Department of Psychology sheds new light on how humans perceive and produce sounds, and may pave the way for investigations into whether motor learning could improve or protect memory or cognitive impairment in aging populations. The research is published in the journal Cerebral Cortex.