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His and her pain circuitry in the spinal cord

New animal research reveals fundamental sex differences in how pain is processed
Mon, 2015-06-29 11:22

New research released today in Nature Neuroscience reveals for the first time that pain is processed in male and female mice using different cells. These findings have far-reaching implications for our basic understanding of pain, how we develop the next generation of medications for chronic pain—which is by far the most prevalent human health condition—and the way we execute basic biomedical research using mice.

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Contact: Chris Chipello
Organization: Media Relations Office
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Office Phone: 514 398 4201

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Contact: Prof. Jeffrey Mogil
Organization: Department of Psychology
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Source Site: /newsroom

Chronic pain alters DNA marking in the brain

Pioneering study reveals association of chronic pain and broad epigenetic changes.
Thu, 2013-02-14 10:25
Injuries that result in chronic pain, such as limb injuries, and those unrelated to the brain are associated with epigenetic changes in the brain which persist months after the injury, according to researchers at McGill University. Epigenetics explores how the environment – including diet, exposure to contaminants and social conditions such as poverty – can have a long-term impact on the activity of our genes.

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Contact: Cynthia Lee
Organization: Media Relations, McGill University
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Office Phone: 514-398-6754
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Source Site: /newsroom