MCGILL UNIVERSITY PROGRAM IN CANCER GENETICS
Research Group, March 2012
The Program in Cancer Genetics is committed to fostering research, grants and data. Our work is detailed in the 2010 Annual_Report.
A Comprehensive Approach to Hereditary Cancer
Human Genetics is now at the forefront of academic medicine. In addition, its applicability to the management of individuals with, or at risk of, cancer has created the sub-specialty of clinical cancer genetics. Hereditary cancer has been a prominent feature of research at McGill University in the last decade. Our mission is to establish in Montreal a leading inter-disciplinary centre for hereditary cancer genetics that will provide an ideal environment for clinical service, research and teaching. Dr. Will Foulkes is a part of the Montreal General Hospital (MUHC) and the Jewish General Hospital. He and his team carry out clinical and research work at both sites.
The Program in Cancer Genetics continues to produce ground-breaking research findings, including "Homozygous BUB1B Mutation and Susceptibility to Gastrointestinal Neoplasia", published in the New England Journal of Medicine, and "DICER1 Mutations in Familial Multinodular Goiter With and Without Ovarian Sertoli-Leydig Cell Tumors" in the Journal of the American Medical Association. Dr. Foulkes's review for the New England Journal of Medicine entitled "Triple-Negative Breast Cancer" was published in December 2010. In September 2010, Dr. Tischkowitz's "PALB2/FANCN: recombining cancer and Fanconi anemia" was published in Cancer Research.
Laboratory research connected with the Program in Cancer Genetics is carried out at:
The Research Institute of the McGill University Health Centre (see website)
Lady Davis Institute for Medical Research (see website)
The Goodman Cancer Centre (see website)
Clinical work is carried out at the following hospital locations:
(cancergenetics [dot] oncology [at] mcgill [dot] ca (email))
Clinical Referral Guidelines for Hereditary Breast and Ovarian Cancer
McGill Hereditary Breast Ovarian Guidelines English [.pdf]
McGill Hereditary Breast Ovarian Guidelines French [.pdf]
Our previous work can be reviewed in our 2009 Annual Report.