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Dan Nicolau

Dan NicolauChair of the Department of Bioengineering
Endowed Professor of Engineering

Ph.D. Polytechnical University at Bucharest, Romania
M.S. Academy of Economic Studies at Bucharest, Romania

Macdonald Engineering Building, Room 375
dan [dot] nicolau [at] mcgill [dot] ca (e-mail )

Research Interests

  • design and fabricate dynamic hybrid nanodevices comprising linear protein molecular motors working on semiconductor manufactured electro-mechanical devices;
  • design and fabricate ‘smart’ micro/nano-profiled and electrically-active surfaces that combinatorially probe the response of biomolecules for micro/nano-array applications;
  • study effective, non-denaturating technologies for immobilization of biomolecules in static (e.g. biosensors) and dynamic (e.g. microfluidics) biodevices;
  • study intelligent-like behaviour and algorithms used by microorganisms in their survival and search strategies, probed in microfabricated structures


  • BIEN 520: High Throughput Bioanalytical Devices (3 credits)

Selected Publications

Protein Molecular Surface Mapped at Different Geometrical Resolutions.
Nicolau, D.V., Paszek, E., Fulga, F., Nicolau Jr., D.V.
PLoS ONE. 2013 March 14; 8(3), Art. No. e58896 DOI: 10.1371/journal.pone.0058896

Separation-free detection of biological molecules based on plasmon-enhanced fluorescence.
Wilson, R., Nicolau, D.V.
Angewandte Chemie – Int. Ed. 2011 February 25; 50(9), 2151-2154 DOI: 10.1002/anie.201005975

The BAD project: Data mining, database and prediction of protein adsorption on surfaces.
Vasina, E.N., Paszek, E., Nicolau Jr., D.V. , Nicolau, D.V.
Lab on a Chip. 2009; 9(7), 891-900. DOI: 10.1039/b813475h

Visit MEDLINE indexed publications for more.