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Julie St-Pierre

Julie St-Pierre

Associate Professor
Department of Biochemistry

Mitochondria, Pgc-1, respiration, metabolism, proton leak, cancer

Rosalind and Morris Goodman Cancer Centre
The Cancer Research Building
1160 Pine Avenue
Office: Room 519; Lab: Room 411
Montreal, Quebec H3A 1A3
Tel: 514-398-3474; Lab: 514-398-2746
Fax: 514-398-6769
julie [dot] st-pierre [at] mcgill [dot] ca

2001 - PhD, Department of Zoology and Trinity College,
University of Cambridge, Cambridge, England

Research Interests

Mitochondria play a central role in basic physiological functions by producing most of the cellular ATP. Furthermore, mitochondria are important for cellular functions such as heat production, generation of reactive oxygen species (ros) and execution of the apoptotic program. Given the key role of mitochondria in various cellular events, it is not surprising that mitochondrial dysfunctions are seen in many pathological conditions such as neurodegeneration, diabetes, aging and cancer. The aim of my research is to understand the regulation of mitochondrial metabolism under physiological and pathological conditions using unbiased screening approaches, notably metabolic profiling in combination with global gene expression analysis.

Publications - Julie St-Pierre