Department of Biochemistry
von Hippel-Lindau (VHL) tumor suppressor
Rosalind and Morris Goodman Cancer Centre
McIntyre Medical Sciences Building
Office and Lab: Room 707B
3655 promenade Sir William Osler
Montreal, Quebec H3G 1Y6
Tel: 514-398-1521; Lab: 514-398-1557
arnim [dot] pause [at] mcgill [dot] ca
1994 - PhD, McGill University
- Molecular characterization of the von Hippel-Lindau (VHL) tumor suppressor gene pathway, identification of new targets of the VHL ubiquitin ligase, mechanism of tumorigenesis in VHL tumors (renal cell carcinoma) and C.elegans, development of animal models of kidney cancer (mice and C.elegans).
- Functional characterization of the Birt-Hogge-Dube (BHD) tumor suppressor protein in kidney cancer and in cellular and whole animal metabolism (mice and C.elegans).
- Functional characterization of a tyrosine phosphatase involved in tumor suppression, studies in cellular and animal models.
Publications - Arnim Pause