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Raj Duggavathi


BVSc, MVSc (University of Agri. Sci., Bangalore), PhD (University of Saskatchewan)
Assistant Professor of Reproductive Physiology

raj [dot] duggavathi [at] mcgill [dot] ca (Raj Duggavathi)
Room MS1-085, Macdonald-Stewart Building
21,111 Lakeshore Road
Ste. Anne de Bellevue, Quebec H9X 3V9

Tel.: 514-398-7803
Lab: 514-398-7596 (MS1-110)
Fax: 514-398-7964

Prof. Raj Duggavathi


Research Interests

  • Mechanisms by which the Nuclear Receptors regulate ovarian functions
  • Metabolic regulation of ovarian functions
  • Transcript variants and ovarian function
  • Ovarian functions including somataic cell proliferation and differentiation; regulation of steroidogenesis; ovulation; corpus luteum development and regression

Research Support

NSERC - Discovery

FQRNT - Nouveau Chercheur

CFI - LOF Individual

Research Trainees

anitha [dot] kalaiselvanraja [at] mail [dot] mcgill [dot] ca (Anitha Kalaiselvanraj) , BVSc (MSc student), "Characterization of Mtor pathway in the ovary”

lisa [dot] dupuis [at] mail [dot] mcgill [dot] ca (Lisa Dupuis) , BSc (MSc student), “Leptin signaling in the ovary”

dayananda [dot] siddappa [at] mail [dot] mcgill [dot] ca (Daya Siddappa) , BVSc, MVSc (PhD student), “Role of Mtor signaling in ovarian function”


Biochemistry 2 (ANSC 234)

Swine and Poultry Production ANSC 458)


Professional Activities

  • Chair – Animal Science Safety Committee
  • Member - Faculty Animal Care Committee

Position Availability

We are always open for new PhD and post-doctoral trainees. Send your CV along with a statement of research interest to raj [dot] duggavathi [at] mcgill [dot] ca (Raj Duggavathi) to discuss funding possibilities.

Publications (2007 - 2009)

Duggavathi R and Murphy BC. 2009. Ovulation signals. Science 324:890-1

Mouzat K, Volat F, Baron S, Alves G, Pommier AJ, Volle DH, Marceau G, Dehaze A, Déchelotte P, Duggavathi R, Caira F and Lobaccaro JM. 2009. Endocrinology 150:3369-75

Bagu ET, Davies KL, Epp T, Arteaga A, Barrett DM, Duggavathi R, Barth A and Rawlings NC. 2009. The effect of parity of the dam on sexual maturation, serum concentrations 1 of metabolic 2 hormones and the response to Luteinizing Hormone Releasing Hormone in bull calves. Reproduction in Domestic Animals (in press Mar 18, 2009)

Duggavathi R, Volle DH, Mataki C, Messadeq N, Antal C, Auwerx J, Murphy BD and Schoonjans K. 2008. The nuclear receptor liver receptor homolog -1 is essential for ovulation. Genes and Development 22:1871-6

Barrett DM, Bartlewski PM, Duggavathi R, Davies KL, Rawlings NC. 2008 Synchronization of follicular wave emergence in the seasonally anestrous ewe: the effect of estradiol with or without medroxyprogesterone acetate. Theriogenology 69:827-36.

Duggavathi R, Bartlewski PM, Barrett DM, Bagu ET, and Rawlings NC. 2008 Short- and long-term effects of unilateral ovariectomy in sheep. Biology of Reproduction 78:490-496

Madgwick S, Bagu ET, Duggavathi R, Bartlewski PM, Barrett DM, Huchkowsky S, Cook SJ, Beard AP, Rawlings NC. 2008 Effects of treatment with GnRH from 4 to 8 weeks of age on the attainment of sexual maturity in bull calves. Animal Reproduction Science 104:177-88

Volle DH, Mouzar K, Duggavathi R, Dechelotte P, Sion B, Veyssiere G, Benahmed M, Lobaccaro JM. 2007 Multiple roles of the nuclear receptors for oxysterols LXR to maintain male fertility. Molecular Endocrinology 21:1014-27

Volle DH, Duggavathi R, Magnier B, Houten SM, Cummins CL, Lobaccaro JM, Verhoeven G, Schoonjans K, Auwerx J. 2007 The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice. Genes and Development 21:303-15.

Barrett DMW, Duggavathi R, Davies KL, Bartlewski PM, Bagu ET, and Rawlings NC. 2007 Differential Effects of Various Estradiol-17beta Treatments on Follicle-Stimulating Hormone Peaks, Luteinizing Hormone Pulses, Basal Gonadotropin Concentrations, and Antral Follicle and Luteal Development in Cyclic Ewes Biology of Reproduction 77:252-62