This area covers a diverse range of technologies, species, applications and environments, ranging from the laboratory to the Macdonald Campus Farm, and both the Small and Large Animal Research Units. With the sequencing of genomes and proteomes now common practice, and the molecular techniques, used to obtain and analyze this information, constantly evolving, much of the research by this group of researchers involves such techniques as somatic cell nuclear transfer, transgenic disease models, and the study of the influence of the environment on genes. Most of these staff are also highly multidisciplinary in their research, developing themes in bioinformatics, biomedicine, stem cells, nutrient-gene interactions, diabetes, toxicology and cancer.
Vilceu Bordignon, Associate Professor; MSc, DVM (Brasil), PhD (Université de Montréal). Animal cloning by nuclear transfer; In vitro embryo production; Reproductive physiology.
Raj Duggavathi, Assistant Professor; B.V.Sc, M.V.Sc. (Bangalore, India), PhD (University of Saskatchewan). Development of models to study roles of a specialized class of transcription factors, nuclear receptors, for efficient domestic animal production
Sarah Kimmins, Assistant Professor; B.Sc. (Dalhousie), M.Sc. (Nova Scotia Agricultural College), PhD (Dalhousie). Linking genes and the environment to health; Studying how toxicants, nutrients and pharmaceutical can act on genes to induce or even prevent disease; Epigenetics; Transgenic animal models; Animal toxicology models; Large scale epigenomic and expression array analysis.
David Zadworny, Associate Professor; BSc, PhD (Guelph). Molecular endocrinology and genetics in poultry and dairy cattle aimed at identifying genes and gene pathways that affect reproduction and production traits.
Xin Zhao, James McGill Professor; BSc, MSc (Nanjing, China), PhD (Cornell). Dairy cattle biochemistry and physiology; Milk synthesis; endocrine-immune reaction; biologically active peptides from milk proteins; neutrophil diapedesis and mastitis.